Health officials say we will likely need a booster shot for the COVID-19 vaccine - KOMO News

[unable to retrieve full-text content]Health officials say we will likely need a booster shot for the COVID-19 vaccine  KOMO News The Link Lonk


May 01, 2021 at 07:16AM
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Health officials say we will likely need a booster shot for the COVID-19 vaccine - KOMO News

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Moderna ramps up investments to triple vaccine output, eyes boosters - Yahoo Finance

The New York Times

Mask On or Off? Life Gets Back to Normal, and We're Rusty.

Mark Rasch hopped on his bike Tuesday in Bethesda, Maryland, pedaled off for an afternoon ride and realized he forgot his mask. As he turned back for it, news came on the radio over his earbuds: The Centers for Disease Control and Prevention said masks were no longer required outdoors for fully vaccinated people unless they were in a crowd. Rasch, a lawyer, rode on, naked from nose to chin for the first time in a year. He reached nearby Georgetown and found he was nearly alone, in that almost everyone else there remained masked. “I wondered if there was a store I could go into without wearing a mask to buy a mask?” he said. Instead, he went home and told his wife, “Nothing is changing, but it’s happening quickly.” Sign up for The Morning newsletter from the New York Times It’s springtime of the pandemic. After the trauma of the past year, the quarantined are emerging into sunlight and beginning to navigate travel, classrooms and restaurants. And they are discovering that when it comes to returning to the old ways, many feel out of sorts. Do they shake hands? Hug? With or without a mask? It’s a confusion exacerbated by changing rules, state and federal, that vary by congressional district or even neighborhood, all while the very real threat of infection remains, in some places more than others. Many states and cities are scrambling to incorporate the agency’s new counsel into their own rules. New York has ended its curfew. In California, where masks remain recommended, authorities are looking to reconcile the clash of cues. “We have reviewed and support the CDC’s new masking recommendations and are working quickly to align California’s guidance with these common sense guidelines,” Dr. Tomás Aragón, director of the California Department of Public Health, said in a statement. Dr. Susan Huang, of the University of California, Irvine, Medical School, explained the conflicted psychology as a function of rapidly changing risk and the difference in tolerance that individuals have for risk. At present, she said, most places have a foundation of people vaccinated but are not near the 80% that marks herd immunity — with no children inoculated. “We’re between the darkness and the light,” Huang said. She likened the psychology around masks and other behavior to the different approaches people take to changing their wardrobes at the end of winter: People who are more risk-averse continue to wear winter clothes on 50 degree days, where bigger risk-takers opt for shorts. “Eventually,” she said, “everyone will be wearing shorts.” It seems that this psychology may come to define the way the pandemic ebbs, revolving less around public dictate than personal comfort after a stark trauma. For many, the jurisdictional battle is internal, with head and heart clashing over the right personal policy. “I have hugged friends but in a very clumsy body posture,” said Shirley Lin, who lives in Fremont, California, where she works on business development at a mobile game company. “The bear hugs with the joyful scream will not be seen for a long, long time.” Her partner lost his mother to COVID-19. She died in August in St. Petersburg, Russia, at age 68. Lin, scarred, is dubious that the risk has passed. “I don’t think we can slack off on the proper social distancing and masking,” she said. But “we are much more optimistic.” Masks have also become so much more than mere barrier between germs and lungs. They can keep that too-chatty neighbor at bay or help the introvert hide in plain sight. And vanity? Goodbye to that. “It saves me having to put on sunscreen and wear lipstick,” said Sara Becker, an associate professor at the Brown University School of Public Health. She recently had an awkward transitional moment when she, her husband and two children went to an outdoor fire pit with vaccinated neighbors. “Someone offered me their hand, and I gave my elbow,” Becker said. She was “not quite ready for handshakes or hugs,” she explained, though “pre-COVID, I was definitely a hugger.” So was Dr. Shervin Assari, but he’s abstaining — at least for now, particularly after the past few weeks. His mother, who lives in Tehran, Iran, was just released from the hospital there after a dangerous bout with COVID-19, and Assari feels chastened anew. “I had an abstract idea about the risk, and now I really see the risk,” said Assari, who lives in Lakewood, California. He’s “half-vaccinated,” he said, “and terribly scared of COVID-19.” Assari, a public health expert, is trying to modulate his own behavior given the three different worlds he’s trying to navigate: the working-class neighborhood where he lives in South Los Angeles; his daughter’s elementary school; and the historically Black medical school, Charles Drew University of Medicine and Science, where he teaches family medicine. Each differs in culture. Most residents of his neighborhood wear masks but also seem to him respectful of individual choice. The elementary school maintains rigid standards with daily checklists to make sure no one is sick or at risk. And at the medical school, people religiously wear masks, even as the school roils with mistrust of the vaccination, despite the fact it trains doctors, nurses and others in the field. “It’s shocking; it’s very deep mistrust, not just moderate,” Assari said. The skepticism of the medical establishment was centuries in the making — like the infamous Tuskegee experiments — and he doubts it will end soon. But the mistrust at his school is different from that of conservatives: Vaccination may be slow among both groups, but white conservatives may be quicker to rip off their masks, if they wore them at all. “There’s none of that Tucker Carlson stuff here,” he said. Carlson, a talk-show host on Fox News, said on a recent show that having children wear a mask outside should “be illegal” and that “your response should be no different than seeing someone beat a kid at Walmart” and to call the police. (Dr. Anthony Fauci, the president’s chief medical adviser for COVID, promptly shot back on CNN, “I think that’s self-evident that that’s bizarre.”) In San Francisco, Huntley Barad, a retired entrepreneur, ventured out with his wife this week, and they took their first walk without masks in more than a year. “We walked down the Great Highway,” he said. “We’re ready to poke our heads out from underneath our rock and perhaps find a restaurant with a nice outdoor table setup — on a warmish night, if possible.” But he said that their plans for a date night weren’t firm, much like the conflicting guidance and behavior of a nation itself. “Nothing definite yet,” he said. This article originally appeared in The New York Times. © 2021 The New York Times Company

The Link Lonk


April 30, 2021 at 03:47AM
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Moderna ramps up investments to triple vaccine output, eyes boosters - Yahoo Finance

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This Testosterone Booster Is Scientifically-Optimized - Men's Journal

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The Link Lonk


April 30, 2021 at 09:53PM
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This Testosterone Booster Is Scientifically-Optimized - Men's Journal

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Moderna CEO: 'We are going to need boosters starting this fall' - Yahoo Finance

The Telegraph

All adults could cut heart attack risk with daily blood pressure pill, study finds

All adults would benefit from taking a daily blood pressure pill to reduce their risk of heart attack and stroke, a study has found. The major review by Oxford University concluded that reducing blood pressure was protective even when it is within what is considered to be the healthy range. In what is being described as a "paradigm shift", the review found that one daily dose reduced the risk of serious cardiovascular disease by around 10 per cent. The results were the same regardless of an individual's blood pressure to start with. The findings, published in The Lancet, indicate that potentially millions who are not currently eligible could benefit from antihypertensive medications including commonly-prescribed drugs such as Ramipril – sold under the brand name Altace – Amlodipine and various beta blockers. Around 14 million people in the UK are thought to have high blood pressure, with five million living with the condition undiagnosed, according to the British Heart Foundation. Medical guidelines say only individuals with high blood pressure – above 140/90mmHg – should normally be considered for antihypertensives. However, the new study of 340,000 people across 48 randomised clinical trials found that the size of an individual's relative increase or decrease in blood pressure determined their risk of heart attack or stroke rather than the level itself. The authors have called for the guidelines to be changed so people are not blocked from receiving antihypertensives simply because their blood pressure is not high enough or because they have not previously suffered a cardiovascular event. Prof Kazem Rahimi, who led the research, told The Telegraph: "Antihypertensive medication is a preventative measure regardless of what your blood pressure is. It is likely that many people are not getting it who need it." The authors stopped short of calling for all adults to start taking the pills, saying there would be significant cost implications for the NHS, and the inconvenience may outweigh the benefit for people with a very low risk of cardiovascular disease . But Prof Rahimi added: "At the population level, if you were to treat everyone you would have an average 10 per cent relative risk reduction. That's great – but it's before factoring in other things." He said many patients currently prescribed antihypertensives take a combination, often up to three medications a day, meaning the protective effect is significantly greater. And he added that doctors should disregard an apparently healthy blood pressure when deciding whether to prescribe the drugs and instead assess a patient's risk of heart attack and stroke using factors such as cholesterol levels, age and evidence of diabetes. Heart disease and stroke are the leading causes of death in much of the Western world, and it is widely accepted that blood pressure medication protects people who have had a prior event from having a second. However, the use of the drugs in people with normal or only mildly elevated blood pressure has been hotly debated, with studies producing conflicting conclusions. For the new analysis, the experts pooled data from 157,728 participants with a prior diagnosis of cardiovascular disease, and 186,988 with no such diagnosis. Each group was then divided into seven subgroups based on levels of systolic blood pressure. After four years' follow-up, 42,324 participants had at least one major cardiovascular event. But for every 5mmHg reduction in systolic blood pressure, the risk of stroke or heart failure fell 13 per cent, ischaemic heart disease by eight per cent and death from cardiovascular disease by five per cent. The beneficial effects of the treatment did not differ based on whether the person had previously had cardiovascular disease. Zeinab Bidel, a co-author and also at Oxford, said: "It is important that people are considered for blood pressure-lowering treatment based on their cardiovascular risk, rather than focusing on blood pressure itself as a qualifying factor for or target of treatment. "We must provide well-rounded guidelines to lower risks for cardiovascular disease that include exercise, nutrition, smoking cessation, and – where appropriate – medication." Prof Sir Nilesh Samani, the medical director of the British Heart Foundation, who was not involved in the study, said: "The benefits of lowering blood pressure are there whether you have pre-existing heart disease or not, and this study shows that lowering blood pressure – even if it is in the normal range – is associated with fewer heart attacks and strokes."

The Link Lonk


April 29, 2021 at 11:34PM
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Moderna CEO: 'We are going to need boosters starting this fall' - Yahoo Finance

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COVID-19 vaccine booster shots might be necessary, local health experts say - Foster's Daily Democrat

As we learn more every day about COVID-19, it seems likely that a third COVID booster vaccine could be in the works.

Both Pfizer and Moderna are already researching a booster vaccine as data seems to indicate the immunities from the first two doses will last about six months.

Dr. David Itkin, an infectious disease specialist at Portsmouth Regional Hospital, said that while there is speculation about a third booster shot, at this point there is no recommendation for that to happen.

"We do not have enough data yet to prove it is a necessary thing we will need to do," Itkin said. "We do not know if we will need an annual (coronavirus) vaccine, like that for influenza."

Latest updates: New COVID guidance for business released; a third of NH residents are fully vaccinated

Itkin said those decisions will not be made by Moderna, Pfizer, Johnson and Johnson or any vaccine producer.

"That decision will be made by the CDC-ACIP (Centers for Disease Control - Advisory Council on Immunization Practices)," said Itkin. "The vaccines went to the FDA (Food and Drug Administration) and got EUA (emergency use authorization) and then they went to the ACIP, who is collecting data and it is they who will determine if a booster should be authorized."

Itkin said the ACIP will look at antibody titers, and their rate of decline.

"They look at the rate of decline to extrapolate out to see when a significant percentage of the population will be below the needed rate to be effective," he said. "The impact of the variants further complicates the science. Which variant will become prevalent? It is a moving target at this point. There is a lot of data to be crunched."

More: Yes, vaccinated people can get COVID-19. 'Breakthrough' cases explained.

"The million dollar question is how long will the immunities from the vaccine last?" said Dr. Artemio Mendoza, an infectious disease doctor at Wentworth-Douglass Hospital. "It is expected from the latest data that we can safely say at least six months. COVID is one of those rolling situations. It is a unique position, a pandemic and we are learning as we go along. We really do not have all the answers. I know both Pfizer and Moderna are facing the same issue here, looking to see when the immunities will begin to wane."

Dr. Evangeline Thibodeau, an infectious disease doctor at York Hospital, said a booster vaccine makes sense.

"We do this for a number of virus changes like the flu," she said. "We have tetanus boosters, used to cement in the duration of the immune system response. We know Moderna and Pfizer likely are persistent for at least six months and then there may be gradual waning of its ability to produce an immune response. So why wouldn't we want that to continue at this point?"

Mendoza said his personal feeling is that a booster shot is coming.

"With the current two-dose regimen, the first acted to prime the body and the second shot was sort of a booster," said Mendoza. "A third booster will make the body recognize the virus and act accordingly for another period of time. It really is not much different from other vaccines, like the flu shot which is needed every year because the virus changes. COVID is also changing, evidenced by the variants we are seeing."

Sununu: NH mask mandate ending but face coverings still recommended

Related: Maine lifts outdoor mask mandate

"This is a pandemic unlike any we have seen in our lives," said Itkin. "To me, we have great minds and are seeing great products. I think discussions like this should not be a cause for anxiety. Instead we should be reassured that we are asking the right questions."

The important thing, said Itkin, is the need for everyone to buy in to the science and to get the vaccine. In some cases, he said that is an uphill battle, and he hopes it changes.

"We need to reach herd immunity, to get back to a semblance of normalcy," he said. "We are moving in the right direction but we are not there yet."

The Link Lonk


April 30, 2021 at 04:01PM
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COVID-19 vaccine booster shots might be necessary, local health experts say - Foster's Daily Democrat

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Moderna says booster shots likely needed in coming years, and reveals new data regarding vaccine storage - WBRZ

CAMBRIDGE, Mass.— Moderna, Inc., the company behind one of the widely used COVID-19 vaccines in the U.S., issued a Thursday news release stating that new data reveals its vaccine can remain stable at temperatures found in refrigerators for as long as three months. 

At present, the mRNA vaccine has approval to be stored in refrigerators between 36 and 46 degrees Fahrenheit for up to 30 days and approval to be stored in the freezer up to seven months at minus 4 Fahrenheit, according to the company.

However, this new data appears to support a three-month refrigerated shelf life for the vaccine.

Should the Food and Drug Administration approve, the new storage temperature could “facilitate easier distribution to doctor’s offices and other smaller settings,” the company wrote in its Thursday press release.

The press release stated, "The Moderna COVID-19 Vaccine is also the only authorized mRNA vaccine that does not require on-site dilution. The Company also announced that it is working on formulations of mRNA-1273 and a next generation vaccine (mRNA-1283) that it believes will extend refrigerated shelf life even further."

The company added that data also reveals, booster shots will likely be needed throughout 2022 and 2023, and it is prepared to deliver the necessary doses.

The company stated, “Today we have announced that our investments in Europe, including Spain, France and Belgium, Switzerland, and the U.S. will allow us to deliver up to 3 billion doses in 2022, depending on the mix of product between primary series of vaccination and variant boosters.”

Moderna says it believes this investment in increased supply is necessary due to an expected significant need for booster vaccinations in 2022 and beyond.

Trending News

In harmony with this need for an increase in supply, Moderna announced new funding commitments to increase supply at its owned and partnered manufacturing facilities, which it expects will increase global 2022 capacity to up to 3 billion doses of its COVID-19 vaccine, depending upon the mix between the authorized Moderna COVID-19 Vaccine at the 100 μg dose level and potentially lower doses of the Company’s variant booster candidates and pediatric vaccines, if authorized.

Moderna says it will use its cash balance to fund these investments, which will allow for a doubling of drug substance manufacturing at a Switzerland-based facility, a more than doubling of formulation, fill and finish and drug substance manufacturing at a Spain-based facility, as well as a 50% increase of drug substance at Moderna’s facilities in the U.S.

The news release went on to state, "When completed, the investments will also result in an increase in safety stock of raw materials and finished product used to deliver committed volumes. The Company will begin making investments at its owned and partnered manufacturing facilities in 2021, with increased production from these investments expected to ramp up in late 2021 and early 2022."

As of Thursday, Moderna raised its 2021 manufacturing supply forecast to between 800 million to 1 billion doses. 

The Link Lonk


April 29, 2021 at 05:18PM
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Moderna says booster shots likely needed in coming years, and reveals new data regarding vaccine storage - WBRZ

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UK COVID-19 Update: Booster Jabs, GPs' 'Breaking Point', 'Healthy' BMI Range Risks - Medscape

These are the UK coronavirus stories you need to know about today.

Booster Jabs Trial

Yesterday, an order for another 60 million more Pfizer/BioNTech vaccine doses for an autumn booster jab programme was announced.

England’s Deputy Chief Medical Officer, Professor Jonathan Van-Tam, told a Downing Street briefing a clinical trial starting this summer would be key to planning the booster programme:
"There's a study that will start in June called COVBOOST, and Professor Faust [University of Southampton] and Professor Snape [University of Oxford], are going to be running this, it will be available to many, many people across the UK because so many of us will have had a course of vaccines by then.

"People will be invited and randomised to different kinds of vaccines as the booster. 

"We'll get an idea then of which gives you the highest boost, which perhaps give you the broadest boost against a range of coronavirus variants, and indeed what the timings look like on that. 

"And that is another reason why the Vaccines Taskforce has invested in contracts with not just one or two manufacturers, but six or seven, so that we have that optionality, so we can always try and do the very best thing, scientifically, within the constraints of what we can realise in terms of supply at the time."
 

GPs 'Reaching Breaking Point'

Latest NHS GP data for England show 4.8 million more appointments delivered in March than February.

BMA GP Committee Chair Dr Richard Vautrey, commented: "So for GPs working 11 or 12-hour days, often leading heroic efforts to protect as many people as possible in their communities against a disease that has had such a devastating impact on all of us, it is heart-breaking and completely demoralising to hear accusations that general practice is not open and that patients are not being seen.

"This narrative, categorically proven wrong by today’s data, is extremely damaging at a time when morale is already reaching rock bottom and many GPs, practice managers and others in the practice workforce are reaching breaking point."

Professor Martin Marshall, chair of the Royal College of GPs, said: "We urgently need more GPs and other members of the practice team to manage increasing workload in general practice. Good progress has been made to encourage medical students to choose general practice, but we also need to see comprehensive plans to keep existing and experienced GPs in the workforce, protecting them from burning out by addressing ‘undoable’ workload, so that we can continue to deliver the high quality care that our patients rely on us for."

BMI Risks

A new UK study in The Lancet Diabetes & Endocrinology found COVID-19 risk increases with a BMI of 23kg/m2, which is considered to be in the healthy range.

Hospitalisation risk rose 5% for each one unit increase in BMI, and ICU admission risk was 10% higher for each unit increase. Worse outcomes were also seen in underweight people with a BMI less than 18.5.

Data were from more than 6.9 million people in England and more than 20,000 hospitalised COVID-19 patients.

Co-study lead, Professor Paul Aveyard, University of Oxford’s Nuffield Department of Primary Care Health Sciences, said: "We don’t yet know that weight loss specifically reduces the risk of severe COVID-19 outcomes, but it is highly plausible, and will certainly bring other health benefits."

In a linked comment article, Professor Krishnan Bhaskaran, London School of Hygiene & Tropical Medicine, said: "Key future research priorities will be to establish whether BMI affects vaccine efficacy, and to understand whether people outside the healthy BMI range (18·5–24·9 kg/m2) are at increased risk of post- COVID-19 sequalae. Further careful epidemiological study of these and other emerging questions will inform the ongoing public health response to this new disease that is likely here to stay."

Fully Vaccinated Freedoms

At last night's Downing Street briefing, Prof Van-Tam, was asked if the UK should follow the US in offering fewer restrictions to people who are fully vaccinated.

"If two people who both had two doses of vaccine and have both served at least 14 days after their second dose, then I would be highly confident scientifically that if they were reputable vaccines then indeed it would be incredibly safe for those two people to meet," he said.

He added: "But we just need to make sure we don’t have to go backwards again on any of this and just hold the line a teeny bit longer."

Prof Van-Tam also said data show "we are at or close to the bottom" of levels of UK COVID cases.

Test and Trace

Today's latest Test and Trace weekly data for England show a 9% decrease in positive cases to 21 April compared with the previous week.

Twenty percent fewer cases were referred for contact tracing.

There was a 16% increase in testing compared to the previous week, mainly due to school testing.

There were 4798 people quarantining in managed quarantine hotels.

Outdoor Masks?

Experts debated the merits of outdoor mask wearing in The BMJ today.

Babak Javid, University of California, San Francisco and colleagues, argue that "wearing masks outdoors, particularly at large outdoor gatherings such as sporting events or other settings where it will be difficult to maintain physical distance for prolonged periods, which may have a low but measurable risk of seeding a superspreading event - as well as normalising mask wearing behaviour in general - will bring benefits in reducing risks during the pandemic phase of COVID-19".

However, Dr Muge Cevik, University of St Andrews and colleagues, disagree, saying: "Less than 10% of reported COVID-19 cases involve outdoor transmission, and those are typically associated with prolonged close interactions or settings where people mix both indoors and outdoors. Moreover, no confirmed sizeable COVID-19 clusters or ‘superspreader’ events have been outdoors-only."

BMJ Patient Editor Amy Price’s husband died from COVID-19. In a commentary article she wrote: "When we run, talk, cough, or sneeze, respiratory droplets are released into the air.

"This is why I wear a mask even outside," she said.

"Regular mask wearing both inside and outside can help us protect each other by reducing spread at the source, even when we don’t know that we’re infected."

Mass Home Testing Questioned

Also in The BMJ, experts argue that mass home testing is "a misguided policy, unlikely to reduce transmission".

Public Health Consultants Angela Raffle and Mike Gill, wrote: "The temptation for people with symptoms to opt for unsupervised, rapid, and lower sensitivity self-testing may lead to false reassurance, as happens with other screening, leading to potential increases in transmission."

The comments follow JCVI Deputy Chair, Professor Anthony Harnden's comments to the  Science and Technology Committee yesterday: "I think everybody’s got to be cautious and just because you’ve been vaccinated, and just because you have a negative lateral flow test, [it] does not mean you’re invincible because these tests are not perfect."

Oxygen Factories for India

The UK's latest aid for India includes three oxygen generation units capable of producing 500 litres of oxygen a minute. The machines are the size of shipping containers.

India's health ministry reported 3645 deaths in the last 24-hour period.

111

The Guardian reported criticism of the Government's refusal to publish NHS 111 coronavirus response service (CRS) training material for England because it is "commercially sensitive".

A spokesperson for the bereaved families' group said the decision showed "a total disrespect to families and our loved ones".

NHS 'Privatisation' Briefing

The campaign group EveryDoctor briefed more than 100 MPs online today on the threat of NHS privatisation.

Consultant Anaesthetist Dr Megan Smith said: "I’ve seen NHS patients bumped from operations to make way for someone who is paying privately. I’ve seen the best equipment reserved for those private patients too. This is not what doctors want and it is not what the public wants. This cannot be allowed to continue."
 

Farewell, Sir Simon

NHS England Chief Executive Sir Simon Stevens is standing down this summer. He'll be made a life peer.

In a statement he said: "Joining the health service in my early twenties was one of the best decisions I’ve ever made, followed three decades later by the privilege of leading the NHS through some of the toughest challenges in its history. The people of this country have rightly recognised the extraordinary service of NHS staff during this terrible pandemic, as well as the success of our COVID vaccination deployment. As the pandemic recedes in this country, the NHS’s track record in advancing medical progress in a way that works for everyone rightly continues to inspire young people to join one of the greatest causes – health and high quality care for all, now and for future generations."

Hancock's Jab

Prof Vam-Tam gave England's 42-year-old Health Secretary Matt Hancock his first Oxford/AstraZeneca jab today at London's Science Museum.

Mr Hancock said on Twitter that it "didn’t hurt at all".

https://twitter.com/MattHancock/status/1387685802545647617

See more global coronavirus updates in Medscape’s Coronavirus Resource Centre.

The Link Lonk


April 29, 2021 at 10:11PM
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UK COVID-19 Update: Booster Jabs, GPs' 'Breaking Point', 'Healthy' BMI Range Risks - Medscape

https://ift.tt/2DVP6sH

Moderna says booster shots likely needed in coming years, and reveals new data regarding vaccine storage - WBRZ

CAMBRIDGE, Mass.— Moderna, Inc., the company behind one of the widely used COVID-19 vaccines in the U.S., issued a Thursday news release stating that new data reveals its vaccine can remain stable at temperatures found in refrigerators for as long as three months. 

At present, the mRNA vaccine has approval to be stored in refrigerators between 36 and 46 degrees Fahrenheit for up to 30 days and approval to be stored in the freezer up to seven months at minus 4 Fahrenheit, according to the company.

However, this new data appears to support a three-month refrigerated shelf life for the vaccine.

Should the Food and Drug Administration approve, the new storage temperature could “facilitate easier distribution to doctor’s offices and other smaller settings,” the company wrote in its Thursday press release.

The press release stated, "The Moderna COVID-19 Vaccine is also the only authorized mRNA vaccine that does not require on-site dilution. The Company also announced that it is working on formulations of mRNA-1273 and a next generation vaccine (mRNA-1283) that it believes will extend refrigerated shelf life even further."

The company added that data also reveals, booster shots will likely be needed throughout 2022 and 2023, and it is prepared to deliver the necessary doses.

The company stated, “Today we have announced that our investments in Europe, including Spain, France and Belgium, Switzerland, and the U.S. will allow us to deliver up to 3 billion doses in 2022, depending on the mix of product between primary series of vaccination and variant boosters.”

Moderna says it believes this investment in increased supply is necessary due to an expected significant need for booster vaccinations in 2022 and beyond.

Trending News

In harmony with this need for an increase in supply, Moderna announced new funding commitments to increase supply at its owned and partnered manufacturing facilities, which it expects will increase global 2022 capacity to up to 3 billion doses of its COVID-19 vaccine, depending upon the mix between the authorized Moderna COVID-19 Vaccine at the 100 μg dose level and potentially lower doses of the Company’s variant booster candidates and pediatric vaccines, if authorized.

Moderna says it will use its cash balance to fund these investments, which will allow for a doubling of drug substance manufacturing at a Switzerland-based facility, a more than doubling of formulation, fill and finish and drug substance manufacturing at a Spain-based facility, as well as a 50% increase of drug substance at Moderna’s facilities in the U.S.

The news release went on to state, "When completed, the investments will also result in an increase in safety stock of raw materials and finished product used to deliver committed volumes. The Company will begin making investments at its owned and partnered manufacturing facilities in 2021, with increased production from these investments expected to ramp up in late 2021 and early 2022."

As of Thursday, Moderna raised its 2021 manufacturing supply forecast to between 800 million to 1 billion doses. 

The Link Lonk


April 29, 2021 at 05:18PM
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Moderna says booster shots likely needed in coming years, and reveals new data regarding vaccine storage - WBRZ

https://ift.tt/2DVP6sH

Coronavirus vaccine booster shots may be necessary to fight future variants, Rutgers experts say - RU Daily Targum

Individuals who have received the coronavirus disease (COVID-19) vaccine may potentially need booster shots after 12 months as well as annual vaccinations to maintain immunity and to protect against variant strains, according to Rutgers experts.

Reynold Panettieri, vice chancellor for translational medicine and science at the University, said the overall effectiveness of the vaccine will likely decline over time, as it does with most others.

“The long-term efficacy of the vaccine to generate immunity will wane since such immunity fades with almost every vaccine,” he said.

One such instance is with the tetanus vaccine, said Stanley H. Weiss, epidemiologist and professor at the Rutgers New Jersey Medical School and the School of Public Health. The Centers for Disease Control and Prevention recommends that adults receive a tetanus booster shot every 10 years to maintain protection.

The COVID-19 vaccine provides immune protection through antibodies and cellular immunity, which is partly due to memory T cells, he said. The protection of each will decline over time, but since the vaccines are so new, it is unknown how long the immune response will last. 

Weiss said that since variations exist in people’s responses to the vaccine, boosters may be needed in order to maintain maximum immunity. Booster shots may also be needed to protect against COVID-19 variants.

“Virus variants are arising that are less susceptible to the immune response to the vaccines developed on the original (wild type) virus,” Weiss said.

Two weeks after the second dose of the Pfizer and Moderna vaccines are administered, immune protection seems to extend to the most common variants in the region. New variants are expected to arise from other regions of the world, which may not be covered by the existing vaccines, Weiss said.

Panettieri said that some common diseases which also require vaccine booster shots are the influenza, hepatitis B and Streptococcus pneumoniae, which is responsible for most cases of community-acquired pneumonia.

The reason that certain vaccines only require one dose while others require several doses is due to the varying mechanisms of action in different types of vaccines, he said. For instance, the mRNA vaccine that is offered by Pfizer and Moderna requires two doses to generate maximal immune protection, while Johnson & Johnson’s viral vector vaccine only requires one dose.

Panettieri said that even though the development of the COVID-19 vaccines occurred at an extraordinary speed, the testing and development process did not cut corners, and the potential need for booster shots is unrelated.

As of now, it is unknown whether the COVID-19 booster shot will be identical to the initial vaccine dose, and it could be from six months to even years before one is needed depending on the individual, he said. Future research hopes to find out when people will need to receive the booster, if at all.

If a booster shot is needed, people should expect extended and expanded protection against COVID-19, Weiss said.

“The studies are ongoing, but this question is critically important and must be addressed,” Panettieri said.

The Link Lonk


April 29, 2021 at 11:48AM
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Coronavirus vaccine booster shots may be necessary to fight future variants, Rutgers experts say - RU Daily Targum

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Natural Testosterone Booster Supplements of 2021 - Men's Journal

Testosterone is produced in both males and females, but this hormone is mainly responsible for regulating many vital processes in men’s bodies. Therefore, it plays a significant role in their life. Testosterone is crucial in developing the sexual characteristics of males. 

A decrease in testosterone levels also causes decreased bone muscle mass, hair fall, mood swings, and weight gain. The bad news is that testosterone production reduces by almost 1% every year after 30 years of age. According to an estimate, men over the age of 45 mostly experience a decrease in testosterone levels. 

The symptoms of low levels of Testosterone can be disheartening, and one might feel depressed. A decrease in testosterone level is also referred to as hypogonadism, which can happen due to some unfortunate medical conditions or injuries that may occur to the testes. 

So, if you want to increase your testosterone level, testosterone Boosters will be the best option for you. Any natural or synthetic substance that can increase testosterone level in males is known as a testosterone Booster. 

These testosterone boosters can help increase the production of testosterone levels in your body to help you enjoy an untiring lifestyle. These boosters are highly effective and loved by their users. 

There are lots of different brands available in the market these days. But what’s important here is to make sure that you opt for the natural ones and not the synthetic ones as they can leave undesired after-effects.

5 Natural Testosterone Boosters:

What Techniques Did We Use to Choose Genuine Testosterone Boosters Brands?

Researchers claim that men over 30s should add testosterone supplements to their daily routine. Many companies claim to provide the natural testosterone boosters, but a few of them are trustworthy. Choosing a natural testosterone booster is a relatively tough task as this is a matter of your health. 

Here we discussed some of the techniques that we adopted to select and verify all products: 

• We tried to find out well-known brands and products in the market. 
• We went through customer reviews to get an idea about the potency and effects of each product. 
• We checked each brand’s official websites to verify that they are committed to their consumers’ health. 
• To check the quality, safety, effectiveness, potency, and other parameters, we performed online surveys and tried to have lots of authentic customer feedback. 
• We checked whether they were steroid-free, natural products or not. 
• Individually studied the ingredients of each product to ensure the potency and safety of the product.  

Top 5 Natural Testosterone Boosters [Full Reviews]

 #1. TestoPrime – Top Rated  

Brand Overview

TestoPrime is an online testosterone supplement that claims the use of all-natural ingredients in its products that can boost testosterone production in your body. It is made of natural formulas to help you regain your energy and stamina. 

As stated on the official website, the product is free from steroids or synthetic ingredients, and experts developed the natural formula. One does not need to consult any doctor before taking it (in case of no particular medical condition) as all the ingredients are natural.

It is formulated in the US and UK for consumers all around the world. Each bottle of TestoPrime contains 120 capsules that are produced from high-quality sources.  

Consistent usage of TestoPrime capsules can:

• Boost your physical and mental energy for untiring function throughout the day, even if you are exhausted after a long day at work. 
• Increase the synthesis of proteins to help develop healthy muscles and burn the excess fat without much effort. 
• Increase the testosterone level to the extent that you feel energetic and optimistic. 

Pros:

• TestoPrime is one of the most effective and safest testosterone products to use.  
• Free from any toxic ingredients
• TestoPrime is made from all-natural and harmless components. 
• It was formulated by experts in the FDA-approved labs of the US and the UK. 
• TestoPrime increases protein synthesis. 
• It helps in losing unwanted fats.
• TestoPrime increases mental and physical health, which in turn increases stamina and libido. 
• Does not need to consult a doctor before using it. 
• 100% guaranteed product to satisfy your needs. 
• It comes with a money-back guarantee for a lifetime, which is great. 
• The product arrives with a guide for the best use. 
• The brand offers free and fast shipping. 

Cons:

• Dosage is distributed over the entire day.  

⇒ Visit the Official Website of TestoPrime for the Best Discount

What Is Testoprime Made Up Of? 

Many essential ingredients used for enhancing testosterone are used in the TestoPrime supplements to help consumers deal with low testosterone levels. 

The ingredients which TestoPrime uses in its products are used by other brands also. Still, the unique fact about TestoPrime is that they produce naturally effective and powerful products by increasing most ingredients’ dosage. 

TestoPrime contains 12 herbal extracts along with other natural sources. Here is the list of ingredients used in TestoPrime: 

• D-Aspartic acid (2000mg) – Luteinizing hormone, also called LH hormone, is a gonadotropic hormone that helps a person gain physical strength by ensuring that Testosterone resides within the body. D-Aspartic acid is an amino acid that produces the Luteinizing hormone in healthy levels within the body, thus improving stamina and strength. 

• Panax Ginseng (8000mg) – One of the most common and ancient ingredients used in China for centuries for wellness and health purposes. Ginseng is powered by many antioxidants that reduces harmful piles, increases energy, and enhance sex drive. By using the Ginseng regularly, one can expect increased performance and decreased stress and anxiety levels. 

• Ashwagandha Extracts (668mg) – The manufacturers claim that the Ashwagandha Extract boosts natural testosterone production in the body. 668mg of Ashwagandha extract increases the metabolic rate to help lose unwanted fats and improve energy and muscle gain. 

• Fenugreek (800mg) – Fenugreek is a well-known ingredient to improve sexual health and is studied for a long time. Studies help in the improvement of sexual health and libido and improve metabolism. 

• • Green tea extract (4000mg) – TestoPrime contains a significant amount of catechins (EGCG) that stop testosterone conversion into harmful DHT. 

• Pomegranate Extract – This ingredient does not specifically target testosterone production, but it increases the blood flow, providing energy and strength. 

• Garlic Extract – Researchers claim that garlic extracts significantly increase the level of testosterone production by increasing blood flow. 

• Black Pepper Extract  – It helps to increase the metabolic rate, thus burns the unwanted fats. It also enhances the activity of other ingredients. 

• Zinc – Enhances the production of sperms. 

• Vitamin B5 – Vitamin B5 is known for its role in increasing metabolism, enhancing testosterone production, improving mood, reducing stress, and increasing libido. 

⇒ Click Here to learn more about the Ingredients of TestoPrime

In What Way Does the Product Work?

• Prevents the reduction of Testosterone – Garlic, Ashwagandha, and Zinc prevent the decomposition of Testosterone into harmful DHT. 

• Boosts testosterone level – Natural ingredients used help in the production of Testosterone. 

• Reduction in Physical anxiety – Ashwagandha used in this product helps reduce stress, increasing metabolism. 

• Burns undesirable fat – The natural ingredients enhance testosterone production and help you become fat-free, enhancing muscular gain. 

• Enhance libido – Most of the ingredients used to enhance libido, thus increasing stamina, performance and promote better sex life. 

Recommended Dose 

It is recommended to take four capsules before breakfast every day. Each bottle of TestoPrime contains 120 capsules sufficient for one month. Make sure you take these capsules consistently for the best outcome.  

What Makes This Brand Trustworthy? 

TestoPrime is one of the most effective and highly recommended products by experts. This brand is unambiguous about the ingredients used in it.  

The product is synthesized from 100% natural ingredients, which makes it harmless.  

If you are looking for increased stamina and strength, you can go for TestoPrime instead of steroids and expensive testosterone therapies. It is the best natural product to boost your physical, mental, and sexual life. 

⇒ Visit the Official Website of TestoPrime for the Best Discount

#2. TestoGen – Best for Sex Drive

Brand Overview

TestoGen is another effective and natural testosterone booster. We realized that the natural extracts used in this product are potent enough to increase testosterone levels. It starts exhibiting its effects on the body within a few days. 

Experts formulate TestoGen in labs in the US and the UK. It is one of the most famous products in the market that help improve sex drive, physical stamina, and metabolism.  

It is manufactured by the company MuscleClub Limited that uses 11 natural ingredients along with other beneficial sources. These ingredients are potent and can significantly increase Testosterone, making you feel like a man without taking harmful chemicals. 

Pros:

• It is a strong product to enhance testosterone levels in the body.  
• The brand claims to use all the natural ingredients. 
• It does not have any harmful effects. 
• Eleven natural ingredients help boost stamina, increase testosterone production, reduce body fats, and enhance libido. 
• You can claim your money within 100 days. 
• The brand provides free and fast shipping worldwide. 

⇒ Visit the Official Website of TestoGen for the Best Discount

Cons:

• It takes a bit more time to show its effects. 
• You can only get it from the official website of the company. 
• The brand offers you to buy the product in bulk quantities only. 

What Is Testogen Made Up Of?

• D-Aspartic acid (2352mg) This ingredient regulates the production of amino acids, which helps in the production of Testosterone. 
• Nettle Leaf Extracts (40mg) – Nettle leaf extract significantly increases the production of Testosterone from natural body cells. It is also known to enhance libido. 
• Magnesium (200mg) – It improves the production of hormones needed to produce Testosterone from enzymatic activity.
• Vitamin D3 (50mcg)  – Vitamin D3 boosts testosterone levels by improving metabolism and supporting muscle and bone health.
• Boron (8mg) 
• Zinc (10mg) 
• Vitamin B6 (20mg) 
• Bioperine (5mg) 
• Vitamin K1 (20mcg) – Vitamin K1 makes your bones stronger, and when your bones become strong, they can absorb more vitamin D that boosts the testosterone level in your body. 
• Fenugreek Extract (40mg) 
• Korean Red Ginseng Extract (40mg) 

⇒ Click Here to learn more about the Ingredients of TestoGen

In What Way Does Testogen Work?

• May enhance your testosterone production – Natural ingredients like D-Aspartic Acid, Magnesium, Boron, Zinc, Vitamin K1, etc., can increase testosterone production by your body. This will gradually improve libido and will help you regain your stamina. 

• Prevents Decomposition of Testosterone – Nettle leaf Extract specifically stops the conversion of Testosterone into estrogen. Thus it makes more testosterone availability which is beneficial for your health. 

• Help boost sex drive – Some ingredients present in it helps a man regain his stamina and improve libido. An increase in testosterone level automatically enhances the physical strength that helps you throughout the day. 

• Improve your lifestyle – Many ingredients present to enhance the activity of other ingredients. These collectively help avoid undesirable fats, enhance the sexual drive, and help regain your focus. Intake of testosterone booster supplements increases your focus to perform well during work or any other activity. 

Recommended Dose 

Each bottle of TestoGen contains 120 capsules that are sufficient to consume during a month. It will be best to take four capsules every day, just twenty minutes before breakfast.  

You should consult your doctor before taking TestoGen with any other medicine as it can be harmful and cause allergic effects.  

What Makes This Brand Trustworthy? 

The natural and steroid-free formula has worked effectively for many consumers. It is one of the most potent testosterone booster supplements.  

The company has a well-reputed place in the market for boosting testosterone levels in the body. Consumers seemed to be satisfied with its functioning and potential. 

Like TestoPrime, these boosters are also lab tested to provide health benefits, and these do not impose any harmful effects on the body of consumers. 

⇒ Visit the Official Website of TestoGen for the Best Discount

#3. Prime Male – Best For Men Over 30 & Libido 

Brand Overview

The Prime Male is yet another innovative approach towards achieving optimal testosterone levels. Primarily designed for men of age forty or above, Prime Male is made up of all-natural ingredients. 

The combined effect of these 12 nutrients that prime male is made up of elevates a person’s overall mood by uplifting their libido, boosting their metabolism and testosterone levels, and increasing their muscle strength. 

The manufacturers of this product are based in the United Kingdom. A company named Popura Limited is making this miraculous product. 

We’d recommend Prime Male over the steroids used by the bodybuilders because contrary to those supplements, Prime male is steroid and stimulant-free. So why not opt for something safe and more potent? 

Pros:

• They ship the product to almost all countries except a few.
• Prime male is free of caffeine.
• The company offers a 90-day refund in case the customer is not satisfied with the purchase.
• It promotes metabolism, muscle strength and gives a lift to your libido.
• It contains all-natural ingredients.
• The product is free from steroids and chemicals.
• Middle-aged or aging men can use it without any worries. It is completely safe.

⇒ Visit the Official Website of Prime Male for the Best Discount

Cons:

• The product is not available in stores; you can only purchase it from the official website.
• Users might find it a bit difficult to manage the schedule of dosage.
• The product is a bit expensive.

What Is Prime Male Made Up Of?

• • Vitamin B6, K2, and D3.
  • Zinc Citrate – 30 milligrams.
  • Nettle Root – it may promote prostate health.

• Mucuna Pruriens – might prove itself to help in managing problems like nervous disorder and infertility in men.

• Bioperine – is said to be a rich source of antioxidants. It prevents the damage that free radicals can cause by eradicating them from the body.

• D-Aspartic Acid Calcium Chelate – is a form of amino acid that deals with testosterone production in the body. This can be one of the reasons why it is found in Testosterone boosting supplements.

• Korean Red Ginseng Extract – it might help in treating erectile dysfunction and boost libido.

• Magnesium Citrate – has several benefits, such as improving heart health, boosting muscle and bone strength, or regulating the process of digestion.

• Luteolin – prevents the conversion of Testosterone into estrogen.

⇒ Click Here to learn more about the Ingredients of Prime Male

In What Way Does the Product Work?

• Boosts testosterone levels – with its natural t-boosting components, it uplifts the testosterone levels.
• Prevents secretion of female hormones – since Prime male contains ingredients like Mucuna Pruriens and luteolin, it prevents the secretion of hormones like estrogen, progesterone, and even prolactin. However, the t-booster supplements that don’t contain these ingredients might promote the secretion of these hormones. If prolactin is released in males, it may lead to enlargement of the breast.
• Promotes overall health – certain ingredients such as magnesium citrate in the supplement are meant to promote overall bone and muscle strength.
• Increase Libido – ingredients such as Korean Red Ginseng Extract are said to increase sex drive and excitement in men.
• Prevents T-levels from decreasing – ingredients such as luteolin function prevent Testosterone’s breaking down into estrogen, resulting in low t-levels and increased female hormone levels.
• It works the best for Aged men – not only for the middle-aged guys, but it also works super fine for those who have crossed the age of 40. Prime Male is not only made to increase sex drive in men, but it also leads them to a fuller life by making them physically fit and stout.

Recommended Dose

Four tablets a day, which means one tablet, four times a day. This is the dose recommended by the manufacturer. It would be better if you take the tablets before your meals and during the daytime.

The standard one-month supply package contains 120 capsules.

What Makes This Brand Trustworthy?

The most important thing about this brand that won our trust is that it is free from any kind of steroids, stimulants, chemicals, or harmful substances. 

The next noteworthy thing about this brand is that it isn’t just limited to increasing testosterone levels in the body, but it also helps in maintaining overall good health. The potent ingredients that it contains provide support to the heart, bones, and body muscles. It might also play a part in lowering a person’s body weight.

⇒ Visit the Official Website of Prime Male for the Best Discount

#4. Testo-Max – Best For Building Muscle

Brand Overview

Like all the other supplements listed in this article, Testo-Max is also made up of natural ingredients and is free from steroids. It is manufactured by a US-based brand named Crazybulk. 

Testo max is said to be an alternative to a typical steroid used by bodybuilders. It is because it has quite similar effects as that of Sustanon – the anabolic steroid, but it is a way safer option than that. 

Testo-Max is basically a dietary supplement that helps you gain your energy back after you have done a heavy workout at the gym and you feel exhausted.  

It helps you level up your lost body strength, uplift your sex drive ad stamina, boost the testosterone level in your body; in a nutshell, it would make you feel more enthusiastic and energetic in all respects.

It contains all the natural ingredients which cause an increase in the testosterone level that we have already discussed—for example, Zinc, Magnesium, Boron, and different vitamins. 

Pros:

• Testo-Max is a natural testosterone booster.
• It is legal to use and a safer option as compared to Sustanon.
• The brand offers free shipping all over the globe.
• It helps you revive the energy lost during heavy workouts.
• The company has a sixty-day refund policy. You can get your hard-earned money back in case of dissatisfaction with the product.
• Easy dosage.
• Since the product is made of 100% natural ingredients, it has no side effects.

⇒ Visit the Official Website of Testo-Max for the Best Discount

Cons:

• A bit pricey product.
• Not available in stores – You can only buy it from the official website.

What Is Testo-Max Made Up Of?

• Vitamins– D3 (50mcg) ,K1 (20mcg) ,B6 (20mcg)
• 40 milligrams of Nettle Extract
• 2352 milligrams of D-Aspartic Acid
• 10 milligrams of Zinc
• 200 milligrams of Magnesium 
• 40 milligrams of Fenugreek Extract
• 8 milligrams of Boron
• 5mg of Bioperine
• 40 milligrams of Red Ginseng Extract

⇒ Click Here to learn more about the Ingredients of Testo-Max

In What Way Does the Product Work?

• Increases testosterone levels – this hormone that is produced in the male sex organ called testes is responsible not only for the sexual drive but also for maintaining overall body strength. 

• Brings D-aspartic acid to its use – unlike other amino acids, d-aspartic acid plays a very different role. The role of stimulating the cells of testicles to promote the production of Testosterone. 

• Releases Testosterone into the bloodstream – nettle leaf performs the job of releasing more and more free Testosterone into the body’s bloodstream.

• Support the immune system – potent ingredients like vitamin D3, K1, B6, and Zinc might improve health by boosting the immune system.

Recommended Dose

The manufacturer recommends taking four tablets daily, ideally 20 minutes before having your breakfast. For the best results, one should take the tablets straight for two months, followed by a break of 1 and a half weeks.

Try not to miss the dose regardless of the fact that you are working out or not.

What Makes This Brand Trustworthy?

Testo max is best known for its reputation among athletes and bodybuilders since it has been in the market for quite a long time. Also, all the ingredients used in the product are lab-verified. 

The product is highly efficient and potent and has the trust of many users. Last but not least, the company takes care of their customers well and never disappoints them with their cooperative behavior.

⇒ Visit the Official Website of Testo-Max for the Best Discount

#5. TestRX – Best for Men Over 40

Brand Overview

Since TestRX works very gently on the body, it can be an ideal choice for men who have crossed the age of 40. The best thing about this product is that it precisely fulfills all the promises it makes, contrary to some brands in the market that make your hopes high at first but then disappoint you with the results. 

The benefits of the product are not just confined to uplifting your sex drive but also to promote your overall well-being. With the nutrients that it contains, you might be able to have nights of better sleep and behave more positively. And, eventually, you are going to feel more energetic and confident than you ever did!

So, you don’t need to worry about your less stamina and low sex drive; these testosterone boosters are going to bring the lost spark of your life back!

Pros:

• The tests and trials that the product has gone through prove that there are no side effects of it.
• TestRX is a product of a reputable brand called Leading Edge Health.
• In order to buy the product, you do not need a prescription from your doctor.
• Best for middle-aged men since the product works very gently.
• The company makes no false claims regarding its benefits.
• The website is easy to navigate so that you can make a hassle-free purchase online.

⇒ Visit the Official Website of TestRX for the Best Discount

Cons:

• Some buyers might find it a bit pricey.
• Vegans may not find it suitable for them because of the small quantity of gelatin that it contains.
• You can’t find the product in stores; it is only available online.

What Is TestRX Made Up Of?

• • Vitamins – B6, K2, and D3.
  • ZMA – aspartic acid and zinc monomethionine combine to form it.

• Extracts of Fenugreek seeds

• 200  milligrams of Magnesium

⇒ Click Here to learn more about the Ingredients of TestRX

In What Way Does the Product Work?

• May increase sperm count – the combination of multiple potent ingredients present in the product may boost stamina, sex drive, and even sperm count.

• Boosts enthusiasm – essential nutrients give you strength and energy to carry out daily life activities more effectively and efficiently, and when you feel energetic, you ultimately feel enthusiastic and motivated.

• Promotes fast recoveries – a weak body takes a long time to recover from any kind of injury; for instance, the injuries you get while working out in the gym. However, TestRX focuses on making your body strong enough to bear these injuries and recover from them fastly. 

• Free Testosterone rises in blood – fenugreek seed extracts promote the release of free testosterone into the bloodstream.

Recommended Dose

It is recommended to take four capsules every day. 2 of them in the morning while having breakfast and 2 of them at night with dinner.

However, the results may vary from person to person depending upon the fact that how nutrient-deficient you are. 

It takes a few weeks for the product to start showing results, depending on your lifestyle. Another important thing to let you know here is that you can’t just depend on the supplement while you just lay in your bed eating junk. To obtain maximum results, you will also need to have a balanced diet and stay physically active.

What Makes This Brand Trustworthy?

Like all the other T-boosters that we have discussed in this article, TestRX also contains natural ingredients and is absolutely free from steroids or stimulants. 

The product is not just focused on making your sex life better, but it also helps you gain your lost confidence back by making you mentally and physically strong with the nutrients it contains.

Last but not least, the company offers you a money-back guarantee if you are not satisfied with the purchase. 

⇒ Visit the Official Website of TestRX for the Best Discount

Important Points to Remember While Choosing These Testosterone Boosters

• What the product is made up of – this was our prime concern. We focused on the ingredients used in the products to make sure that everything used in it is natural and has no side effects.

• Recommended dose – we checked the manufacturers’ official websites to have first-hand knowledge about the dosage. 

• User Policies – before we recommended any product to you, we made sure that the brand has suitable policies (such as refund and shipping policies) for its users. 

• Price – this is yet another important factor that we had to keep in mind. Although the products mentioned in our article are a bit pricey, they are all worth it. It is better to make a one-time investment rather than bearing the adverse effects of substandard products trying to save some bucks.

Types of T-Booster Methods of Intake 

Testosterone boosters have different types based on the methods of intake.  

These May Include:

• Infusing Testosterone 
• Transdermal Testosterone 
• Testosterone Capsules 

Infusible or Injectable Testosterone 

Isolated testosterones such as testosterone undecanoate and testosterone cypionate are used in injectable testosterone boosters, which are administered to a person with low levels of testosterone. These chemicals can be injected into the buttock.  

Transdermal Testosterone  

Transdermal Testosterone is the medication given to the person to increase the production of testosterone. Transdermal medications can be directly applied to the skin’s surface (gel, ointment, or cream).  

These medications are applied to the skin, which is then absorbed by the body and enters the bloodstream, improving testosterone production.  

We have found that the recommended starting dose for a person is 4 mg during 24 hours. The person can apply this to the abdomen, back, thighs, or upper arm. 

Do not apply over a topical cream, which may decrease the amount of testosterone absorption by your body. 

Testosterone Capsules 

This one happens to be the easiest way of all. Consumers can directly take oral testosterones or capsules. This type of medication can either be swallowed or chewed with the food or as prescribed by the doctor. The dosage depends on your condition and lab reports. 

Overdosage of the supplement is never recommended. Do not misuse the testosterone capsules as they may lead to heart attacks, liver damage, or strokes.  

Testosterone develops the secondary sexual characteristics, keeps the hormonal balance within the body, and plays a significant role in developing the musculoskeletal system. 

The deficiency of testosterone in male bodies is called testosterone deficiency syndrome (TD) or Low-T, which means that the body does not have sufficient Testosterone.  

The testosterone level decreases with age, and the most common symptoms known are fatigue, depression, irritability, low sex drive, the reduced muscular mass, etc.  

The easiest solution to this problem is to choose a natural and effective testosterone boosting supplement. Testosterone boosters enhance your body’s functioning, but it is not an easy task to choose one. Many brands are out in the market selling different kinds of Testosterone Boosters, but it is hard to predict if they are good to go. 

What Can A Testosterone Booster Do for You? Why Should You Take Them?

If you feel like your life is getting dull day-by-day due to the age factor or if you don’t feel like doing anything productive, a testosterone booster might help you get the spark of your life back by making you energized and healthy with the natural and potent ingredients it contains.

Testosterone is not just responsible for boosting your libido; it performs a number of other vital jobs such as maintaining bone and muscle strength, promoting the production of sperms and RBCs.

So, if your testosterone level is low, who will perform the job it does? Hence, testosterone booster might be necessary once you notice the low t-level symptoms. The best thing about these T-boosters is that they leave no side effects.

Are Steroids and Natural Testosterone Boosters the Same?

The answer to that is a straight NO. There is no way that they can be the same since steroids use artificial methods to boost testosterone levels, whereas natural boosters, with their nutrients, promote a balanced Testosterone Level and also focus on a person’s overall well-being.

Natural supplements help the body to bring the existing testosterone levels to the best use. Most of the natural T-booster contains Fenugreek seed extract that promotes the releasing of free Testosterone into the bloodstream. 

Other nutrients such as nettle leaf and d-aspartic acid promote Testosterone’s natural production, contrary to the synthetic t-boosters that release artificial hormones in the body.

How Do You Know If Your Testosterone Level Is Low?

Before you opt for any t-booster, you should be aware of the symptoms. Low T-level symptoms might include:

• Low libido.
• Difficulty in getting erections.
• Feeling tired most of the time.
• Unwillingness to perform even the smallest and easiest tasks.
• Getting obese.
• Being sluggish.
• Having a hard time remembering things.
• Loss of body mass.
• Less stamina. 

Are Testosterone Boosters Legit?

Yes. They work. But the results may vary from person to person depending on their lifestyle and work schedule.  

Following are the main tasks that testosterone boosters might do for you:

• Releasing free Testosterone in the bloodstream 

• Maintaining a balance of hormones – men also possess female hormones but in a very low quantity compared to Testosterone. An imbalance in these hormones can lead to low libido and stamina in men. So, the testosterone boosters help with that too.

What Are the Benefits of Testosterone?

• It makes your heart healthy.
• It Increases your sex drive.
• It builds your stamina.
• It makes your muscles and bones stronger.
• It enhances your brain function and uplifts your mood.

FAQs About Natural Testosterone Boosters

Q. Is It Safe to Use T-Boosters?

Natural testosterone boosters are safe to use unless and until they are actually natural and free from steroids or stimulants. Not all brands deliver what they promise, and that’s what makes them unreliable. 

So, we advise you to opt only for reputable brands, no matter if it costs you some extra bucks. If you have a particular medical condition or are on some kind of medication, you must consult your doctor.

Q. Do All The T-Boosters Contain Steroids?

No, not all of them. The natural ones are free from steroids. 

Q. What Is the Fastest Way to Boost T-Levels?

The best way to get your t-levels increased is to be consistent. Whenever you opt for a natural t-booster, make sure that you have gone through the instructions given by the manufacturers of the product. After understanding the guidelines, follow them precisely to obtain maximum results.

Conclusion 

Dropping testosterone levels over time is natural. When you have entered or crossed your 40s, you are more likely to suffer low testosterone level symptoms. In such circumstances, you go for the natural solution, which is Natural Testosterone Boosters. 

These boosters are not just meant to increase your sex drive, but they also work to make you feel more energetic to lead towards a fuller life. Our top 2 testosterone boosters are TestoPrime and TestoGen.

Another noteworthy thing about the natural t-boosters is that they have no side effects. However, don’t forget to consult your doctor if you are suffering from any particular medical condition as what worked for us might not work for you.

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The Link Lonk


April 29, 2021 at 03:17AM
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Natural Testosterone Booster Supplements of 2021 - Men's Journal

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